Buspirone is used to treat anxiety disorders and less commonly to treat symptoms of premenstrual syndrome.
Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.
 Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. | Kava |
| Depletion or interference | None known |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Interactions with Herbs
Kava(Piper methysticum)
Kava is an herb used to treat anxiety disorder. Although no direct interactions have been reported, buspirone should not be used together with kava unless with medical supervision.
Interactions with Foods and Other Compounds
Food
Food reduces metabolism of buspirone, increasing serum buspirone levels.1 Buspirone should be taken at the same time each day, always with food or always without food.
Alcohol
Buspirone may cause drowsiness and dizziness.2 Alcohol may compound these effects and increase the risk of accidental injury. To prevent problems, people taking buspirone should avoid alcohol.
References
1. Gammans RE, Mayol RF, LaBudde JA. Metabolism and disposition of buspirone. Am J Med 1986;80:41–51.
2. Threlkeld DS, ed. Central Nervous System Drugs, Antianxiety Agents, Miscellaneous Agents. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1990, 262–c.
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2006-09-07
