Combination drug: Tavist-D
Clemastine is an antihistamine used to relieve allergic rhinitis (seasonal allergy) symptoms including sneezing, runny nose, itching, and watery eyes. It is also used to treat itching and swelling associated with uncomplicated allergic skin reactions. Clemastine is available in nonprescription products alone and in a combination formula to treat symptoms of allergy, colds, and upper respiratory infections.
Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.
 Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results. | Henbane* |
| Depletion or interference | None known |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Reduced drug absorption/bioavailability | None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Interactions with Herbs
Henbane (Hyoscyamus niger)
Antihistamines, including clemastine, can cause “anticholinergic” side effects such as dryness of mouth and heart palpitations. Henbane also has anticholinergic activity and side effects. Therefore, use with clemastine could increase the risk of anticholinergic side effects,1 though apparently no interactions have yet been reported with clemastine and henbane. Henbane should not be taken except by prescription from a physician trained in its use, as it is extremely toxic.
Interactions with Foods and Other Compounds
Alcohol
Clemastine causes drowsiness.2 Alcohol may intensify this effect and increase the risk of accidental injury.3 To prevent problems, people taking clemastine or clemastine-containing products should avoid alcohol.
References
1. Blumenthal M, ed. The Complete German Commission E Monographs. Austin, TX: American Botanical Council, 1998, 146.
2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 191c.
3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 191c.
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2006-09-07
