Ribose is a type of sugar normally made in the body from glucose. Ribose plays important roles in the synthesis of RNA, DNA, and the energy-containing substance adenosine triphosphate (ATP).
Ribose has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Rating | Health Concerns |
|---|---|
 | Angina |
 | Athletic performance |
 Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit. | |
Who is likely to be deficient?
Ribose is not an essential nutrient, therefore deficiencies do not occur.
How much is usually taken?
Sports supplement manufacturers recommend 1 to 10 grams per day of ribose.
Are there any side effects or interactions?
No known side effects have been reported from the use of ribose when consumed in amounts of less than 10 grams per day. Larger amounts may cause gastrointestinal distress such as diarrhea,1 and may lower glucose levels,2 although it is not known whether symptoms of hypoglycemia might result.
References
1. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205–13.
2. Gross M, Zollner N. Serum levels of glucose, insulin, and C-peptide during long-term D-ribose administration in man. Klin Wochenschr 1991;69:31–6.
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2006-09-07
